In November 2014, the lead researcher’s interest in the conceptual development of digital technology and her cultural connection to Indigenous Knowledge Systems created an opportunity to explore a culturally relevant use of technology with urban Indigenous youth: the Indigenous Robotics Prototype Workshop. The workshop achieved a sense of cultural pride and confidence in Indigenous traditional knowledge while inspiring the youth to continue with their engagement in coding and programming through building robots. Yet, the outcomes from the prototype workshop further revealed a need to investigate how Indigenous Knowledge Systems, and particularly Pattern Thinking, might hint toward a possible paradigm shift for the ethical and advanced design of new technologies. This article examines the implications of such a hypothetical shift in autonomous systems in robotics and artificial intelligence (AI), using the Indigenous Robotics Prototype Workshop as a case study and springboard.